The story starts off in the beautiful locales of Hrishikesh in Uttarakhand, where we are introduced to two sisters. Two sisters who are everything for each other since their parents passed away when they wer e kids. Two sisters who can go to ends of the earth and back for each other. One, who has loved the younger one just as a mother would love her child. Jeevika and Maanvi Chaudhary. Jeevika, the elder one, is a teacher, and is a very patient and soft person, while Maanvi, the younger sister is the loud and hyper person.
As Jeevika becomes of age, she starts getting suitors. One of these prospective suitors include Dr Manan, who has been a family doctor for the Chaudharies, and has a soft corner for Jeevika. However, fate had some other plans for Jeevika, and a famous lawyer from Chandigarh comes over to see Jeevika, much to Maanvi's chagrin. This famous lawyer is none other than Viren Singh Chaudhary, who has come along with his younger brother Virat Singh Chaudhary to meet Jeevika. However, as the two sisters go to meet the brothers, both Virat and Maanvi exchange identities and pretend to be their siblings to ensure that their prospective jeeju/bhabhi is suitable for their siblings. Despite all of this, Viren agrees to the alliance, much to Maanvi's chagrin. However, Viren and Virat had figured out that the sisters had exchanged identities for the occasion, and Viren had realised that he had actually fallen for the correct sister. The roka (pre engagement ceremony to officiate the alliance) is to be held at the Vadhera family's Mussoorie house.
All the way to Mussoorie (and in the place itself), Maanvi tries her best to sabotage the relationship, but she comes to realise that her sister cannot find a better husband and life partner than Viren, which is when she accepts her sister's choice and happily takes part in the roka. All the while in Mussoorie, Virat and Maanvi are at loggerheads with each other as they can't seem to stand the sight of each other. It is in Mussoorie during the pious occasion of Karva Chauth that Maanvi is shown to faint for the first time, hinting at the fact that she doesn't keep well. However, as a result of Maanvi's previous attempts to sabotage her sister's alliance, Manan lands up in Mussoorie, much to Virat's suspicion, who realises that something is off. He then tells brother about this, who gets quite annoyed. However, when the Chaudharies come over to Chandigarh to celebrate Diwali with the Vadheras, Maanvi comes clean to Virat about her deeds and the two of them join hands for the first time to patch up Viren and Jeevika.
Very soon, the families gear up for the wedding of Viren and Jeevika. It is during this wedding that the audience realises that Virat is a very good singer, but due to some incident in his past, he has completely given up on singing and he's quite a bitter person. After a few ups and downs during the course of the ceremonies, the wedding finally takes place with pomp and Jeevika moves into her new home.
Amidst a lot of fun and frolic and getting into sticky spots, Viren, Jeevika, Virat and Maanvi spend some wonderful moments with each other (including New Years eve), during which the Chaudharies come to realise that Maanvi is suffering from leukemia. In the meanwhile, Maanvi tries to win the hearts of all the Vadheras. Along with Virat, she manages to help Inder Chachu overcome his problem of stammering and thus wins the heart of Dadaji. At this point, Maanvi and Virat realise they make an awesome pair, and promote each other to "partners".
To try and get into the good books of Swamini, Maanvi helps her to try and patch Virat up with his ex-girlfriend. Virat had dumped Maya due to her brash and cold nature, but Maanvi manages to make Maya pretend as if she's changed. After successfully managing to convince Virat about getting back with Maya, she gets back to Chandigarh as she's already aware of her Cancer by this point. Virat, however, can't seem to get Maanvi out of his head, and keeps calling/texting her. Viren doesn't like Maya too much and he comes to realise that his brother has actually fallen for his saali sahiba. After Maya's truth comes out to Virat, Viren manages to make Virat realise that his true love is his partner, his Maanvi, on which Virat decides to go to Hrishikesh to tell Maanvi his feelings about her.
Maanvi, on the other hand, is fuming because Virat broke up with Maya and refuses to listen to him. The one time Virat manages to fess up to her, she faints on him and his feelings remain unheard. While trying to help Madan Chachu, Virat accidentally sets fire on the family shop, because of which Maanvi's anger knows no bounds and she refuses to talk to him. Viren and Jeevika come down to help the family set up the shop, and Viren pretends to fight with Jeevika to try and help Virat get back with Maanvi. Once the shop is done and Maanvi's forgiven Virat, all decide to go on a picnic, but it is in this fated picnic that Jeevika meets with a fatal accident. Jeevika is in dire need of blood and the only person who can donate blood to her is Maanvi, who is unable to do so because of her cancer. Viren and Virat blast Maanvi for not donating blood to her sister, when she spills the beans to Virat about her leukemia. Viren takes Jeevika back to Chandigarh for better treatment after a blood transfusion (the blood was from Maanvi's emergency stock); and Virat takes Maanvi along so that she can meet her sister. Since Viren is being very cold and not even letting Maanvi look at Jeevika's face, Virat tells his mother, Bua and Viren about Maanvi's cancer, and all sympathize with her.
Jeevika learns that Maanvi has been hiding something from her, and a very reluctant Maanvi soon tells Jeevika the truth about her Cancer on her birthday. Jeevika puts up a brave front in front of Maanvi but breaks down in front of Viren, and the two decide to do all that they can to save Maanvi. Virat comes across and old friend of his who is now a cancer specialist in Mumbai, and the Vadheras and Chaudharies decide to take Maanvi to Mumbai for treatment. All the while in Mumbai, certain incidents take place which make Maanvi rethink her feelings for Virat. Finally, Maanvi comes to realise that she has fallen in love with Virat, and at the same time the doctor tells Virat that Maanvi's body is not suitable for the special treatment that they specialise in, and she has to continue with her older treatment. On Badi Beeji's insistence, Maanvi wants to tell Virat about her feelings but realises that she may not have a very long life, and hides the truth. Virat too hides the truth about the severity of Maanvi's cancer (except to Viren) and all go back to Chandigarh. After a particularly heavy chemo session, Maanvi loses all of her hair. Unable to see Maanvi in such pain and trauma, Virat shaves off his head in front of her. While this encourages Maanvi and stumps Viren-Jeevika, the rest of the Vadheras are not pleased with Virat's decision. During an argument with his family, Virat blurts out his feelings for Maanvi in a fit of rage, which is overheard by Maanvi herself. While the news delights her, she knows she can't be with him cause of her disease, cause of which she decides to leave for Hrishikesh that very night. She also fesses up to Jeevika about her feelings towards Virat, who by this time has begun to support their possible alliance.
While in Hrishikesh, Jeevika lets slip to Viren about Maanvi's feelings, who indirectly lets Virat know about the same. Virat takes off for Hrishikesh and vows to make a stubborn Maanvi confess her feelings in the next 7 days. While he garners support from most of the Chaudharies (sans Beeji who is worried about the Vadhera's reaction). On the last night, Virat stands out in the rain protecting a lone leaf that is supposed to symbolise Maanvi's fragile life, and that is when Maanvi relents and fesses up to him and the two finally unite.
Virat returns home and wants to tell his family about his and Maanvi's relationship when Viren steals his thunder and he announces that Jeevika is carrying their child. After a while, Virat does manage to inform the family of his and Maanvi's love, but they strongly oppose the relationship. Saddened by the thought, the two decide to part ways, but soon the family comes around and all go off to Hrishikesh on the occasion of Raksha Bandhan and ask for Maanvi's hand. The roka is conducted on the very next day, and soon all leave for Chandigarh for the engagement ceremony.
Post the engagement ceremony, Virat tells the family about Maanvi's deteriorating health, and everyone tries to find ways to save Maanvi. The doctor comes up with the idea of a bone-marrow donation to save Maanvi's life, and they even find a donor, but to their ill fate, after Maanvi's marrow has been removed, there seems to be an issue with the donation and it has to stop. Maanvi has only a few days on her, and this is when Jeevika decides to abort her baby and donate marrow to her unborn baby. While Viren is initially against the idea, he comes around and supports her, but Maanvi is strictly against the idea. Maanvi files a case against Jeevika regarding the same and Jeevika finally "agrees" not to abort the kid and the case is closed. What the Vadheras don't know is that Jeevika and Viren secretly underwent an abortion and Jeevika donated marrow to Maanvi as an anonymous donor.
After the operation. Maanvi and the rest of the family find out the truth and are initially furious and grieved, but all understand their position and soon preparations begin for Virat and Maanvi's impending wedding. During this, Jeevika has decided to punish herself, which is why she tries to run away on the day of Virat and Maanvi's wedding. However, Virat manages to convince her and bring her back and the two get married happily.
Post the wedding, the Vadheras find out that the Chaudharies have gone bankrupt and their house is up for auction. The foursome rush to save the house but are unable to do so, and a Karan Shekhawat lands up buying the house, but returns it back to the Chaudharies. He claims that his father was an old friend of Mahesh (Jeevika-Maanvi's father) which is why he is doing this for them, and all are satisfied with this explanation except Viren. Back in Chandigarh, Virat decides to take part in a singing competition and get selected through the auditions. Maanvi gets excited to meet the judges since they're her favorite singers and in a chance audition, she lands up getting through the auditions as well. The family is elated for them, and the two go off for a honeymoon in Mumbai. While in Mumbai, they run into Karan once again, and Maanvi spots Swamini's photo in his room. She gets suspicious, and on doing a LOT of snooping around, she realises that Karan is Swamini's estranged son. All the Vadheras warmly welcome him home but once again, Maanvi hears him talking to Viren's old enemy -Jaiswal- and she begins to mistrust him again. During this, Virat and Maanvi take part in the various rounds of the singing contest and are pitted against each other, which creates a rift in their relationship. On the day of the finals, the two decide to throw their ego aside and forfeit the contest.
After some more snooping around by both the sisters, Jeevika and Maanvi come to realise that Karan is working with Jaiswal to destroy the Vadheras, and the ladies go to ambush Karan. While in the middle of a heated physical fight, a bullet supposedly is fired from the gun in Jeevika's hand and Karan dies. Virat arrives on the location and decides to take the blame on his own head and forces Jeevika not to open her mouth. The family is in grief as they can't understand what has happened, when Jeevika comes clean and tells the truth to the family as well as in the court. While trying to fight the case, Viren manages to prove that it was actually Jaiswal who killed Karan, and not Jeevika or Virat. To celebrate this happiness and to cheer up a depressed Swamini, the Vadheras go off on a picnic. It is towards the end of this picnic that Swamini finds out the harsh reality about her son and gets a heart-attack,
Viren is shocked at the turn of events and blames Jeevika for Swamini's state as he'd asked her to never tell her the truth. The misunderstandings between the two increase to such an extent that Jeevika leaves the house and returns to Chandigarh. Virat and Maanvi come to realise what has happened and follow her to bring her back; and it is during this time that Dabboo's wedding gets fixed. On the occasion of Dabboo's engagement, Viren makes an appearance, much to everyone's delight and that's when Virat-Maanvi begin to play cupid by pretending to want a divorce to get Viren-Jeevika to come together to sort out their issues. However, Viren and Jeevika sort out their issues on their own and play a prank on Virat-Maanvi and pretend to get them divorced. But as they say, all's well that end's well; and everyone's truth comes out on the day of Dabboo's wedding, and Swamini and Jeevika bury their hatchet.
On returning back, Virat takes it upon himself to become a successful singer. He tries auditioning for many composers and audio labels, but is either rejected for someone with "star connections" or favored cause he's Viren Singh Vadhera's brother. To ease his frustration, Viren gets a friend of his to sign a contract with Virat and launch him in an album, but on the day the contract is supposed to be signed, Virat finds out the truth. He is hurt and angry, and decides to leave the house; and Maanvi follows him. The two of them move into the Vadhera outhouse and begin a little life of their own. The two sisters pine for one another, while Viren and Virat are furious. In a bid to earn money, Virat agrees to tutor a little kid as he waits for a successful audition. During this, Maanvi meets with an accident and breaks her hand, which prompts Jeevika to disguise herself as a household help Dhanno, to help Maanvi with her work. After a lot of drama on Maanvi's birthday and on Holi, Virat finally gets a contract purely on his merit, and the siblings reunite and Virat-Maanvi return back to the Vadhera Mansion.
It is then that Viren comes across an old friend of his; Sambhav who is married to Riya. The two of them catch up over old times, and Viren comes to realise that Riya seems to be suffering from a mental ailment. Sambhav and Sheetal [who's masquerading as Riya] are plotting to kill Riya [Sambhav's actual wife] and trap Viren in the crime. They succeed in doing so, and get Viren jailed for the crime. However, after a lot of sleuthing by Jeevika, Virat and Maanvi, Viren is proved to be innocent and he returns home.
During this time, Jeevika and Maanvi figure out that Sweety has ulterior motives behind getting married to Dabboo, and plans on capturing the entire property. This prompts Maanvi and Jeevika to return to Hrishikesh [soon to be followed by their loving husbands] where the two sisters and their husbands try various ways to reform Sweety. Finally, Sweety realises her mistake and reforms her ways, and the foursome return to Chandigarh.
Virat begins to contact more composers and directors for offers, while Viren-Jeevika decide that they want to conceive. Despite many tries, they realise that Jeevika is not able to conceive and upon consultation, the doctor reveals that she's suffering from a medical complication which makes it difficult for her to conceive naturally. Even though the family is upset, they decide on taking the suggested treatment followed by an IVF procedure in order to conceive. It is in the middle of this mayhem that Maanvi realises that she has conceived, much to everyone's surprise and delight, except Virat, as they had not planned for a baby.
While Virat takes some time to accept the fact that he's becoming a father, Viren and Jeevika are in a for a rude shock as they are informed that Jeevika can never conceive due to certain complications. The entire house is supportive of Jeevika and are trying to motivate her; and Maanvi even tries to make Jeevika take her unborn baby as her own, but Jeevika and Viren want a child of their own. It is then that they decide to opt for surrogacy, and a lovely young girl by the name of Vidhi enters their life and agrees to be their surrogate.
In the midst of this, Virat and Maanvi have a huge fight as in the heat of a misunderstanding, Virat tells Maanvi that he doesn't want a kid and is not ready to be a father as his career has only just begun to take off. A shocked and broken Maanvi returns to Hrishikesh without telling anyone, only to be followed by Virat, who has now realised his folly. Maanvi however, is quite adamant about her decision to live away from Virat; and only after a lot of cajoling and coaxing, does she agree to give him one last chance. Virat pretends to take care of a life like baby doll, and finally manages to win back Maanvi's trust and love.
However, in the middle of this, it is revealed that Vidhi is secretly married and has begun to have feelings for Viren, who is excessively caring towards her. Vanshikaa notices this, and after showdown between the two women, Virat and Vanshikaa manage to bring Vidhi back after understanding one another. This is when Virat leaves for his world tour as he's now become a successful singer.
Maanvi, in the meanwhile, happens to meet a fun loving man who's just like her, and introduces himself as Monty. The two of them bond while in the hospital [Monty is there for dialysis while Maanvi goes for regular check ups pertaining to her pregnancy] and in other situations and Maanvi motivates Monty to go back and try reconciling with his estranged family. It is then revealed that Monty is actually Jeevika-Maanvi's father, Mahesh. Mahesh had walked out on his wife and his family, which caused their mother to die of heartbreak. Mahesh is now repenting for his sins, but Beeji is unwilling to forgive him. In a huge showdown, Maanvi realises that Mahesh is her father, which completely shocks her. However, she forgives him and soon gets Beeji and the rest of the Chaudharies to forgive him as well.
On the other hands, a man called Harshad comes in to the Vadhera house, pretending to be Viren's childhood friend. In reality, he is Vidhi's abusive husband who is only in the house to try and loot the Vadheras and torture Vidhi. Viren comes to know of his truth and begins to always be around Vidhi to protect her [and their child] from Shashank/Harshad. Jeevika misinterprets this as Viren's love for Vidhi, and she decides to leave the house. When this happens, Viren-Vidhi come clean to her with the truth, and she herself goes and slaps Shashank and protects Vidhi. In a major showdown, Viren beats the living daylights out of Shashank, gets him to sign divorce papers and gets him arrested.
Maanvi and the Chaudharies return to Vadhera Mansion on the occasion of Raksha Bandhan, and Maanvi introduces Mahesh to the Vadheras. Jeevika is initially unwilling to accept her father cause of what all he'd done to them, but when he saves Maanvi's life by risking his own life, she forgives him and the family is reunited.
The show takes a short leap of 6 months, and Maanvi and Vidhi are due for delivery. Vidhi falls down the stairs and is rushed for an emergency delivery by Viren, Swamini and Vanshikaa. The doctor reveals that there's a major complication, and either the baby or the mother can be saved. Jeevika [who's at a faraway mandir with Virat-Maanvi] is told of the news and with a heavy heart she asks the doctor to save Vidhi. At the same time, Maanvi's water breaks and she has to undergo an emergency delivery. With no hospital nearby, Virat and Jeevika take her to the pujari's house where Jeevika helps Maanvi deliver her baby, a girl. At the same time, Vidhi's delivery is successful and she's saved, and she gives birth to a little baby girl.
The show takes another one month leap to the christening of the two newborns; Vidhi has left the Vadheras for good and promises to return. Virat and Maanvi name their daughter Jaanvi, as it was cause of Jeevika that Maanvi's life is what it is. Viren and Jeevika name their daughter Maansi -Maanvi jaisi- as they claim that they want their daughter to be a replica of their first daughter- Maanvi. The sister sing the title track to one another after Maanvi publicly thanks Jeevika for all what she's done for her; and then Virat-Maanvi and Viren-Jeevika dance to some popular Bollywood numbers. The show ends on a high note with the two couples and their families dancing Bhangra ala the traditional Punjabi style.
